Reactome | LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1

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LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 Show undefined attributes

catalystActivity	[CatalystActivity:10209652] epoxide hydrolase activity of LTA4H:Zn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10209685
displayName	LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1
eventOf	[Pathway:R-RNO-9018681] Biosynthesis of protectins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9020257] LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 - Homo sapiens
input	[SimpleEntity:R-ALL-9024893] 17R(16)-epoxy-DHA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1
output	[SimpleEntity:R-ALL-9024879] AT-(N)PD1 [cytosol]
precedingEvent	[Reaction:R-RNO-9020262] ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9020257
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9018681] Biosynthesis of protectins
(inferredTo)	[Reaction:R-HSA-9020257] LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1

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