Reactome | Intracellular signaling by second messengers

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222477
displayName	Intracellular signaling by second messengers
eventOf	[TopLevelPathway:R-RNO-162582] Signal Transduction - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-1257604] PIP3 activates AKT signaling - Rattus norvegicus [Pathway:R-RNO-1489509] DAG and IP3 signaling - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9006925] Intracellular signaling by second messengers - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	7
name	Intracellular signaling by second messengers
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9006925
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-RNO-162582] Signal Transduction
(inferredTo)	[Pathway:R-HSA-9006925] Intracellular signaling by second messengers

Cite Us!