Reactome | ALOXE3 isomerises 12R-HpETE to HXA3

Schema > Reaction > Entries

ALOXE3 isomerises 12R-HpETE to HXA3 Show undefined attributes

catalystActivity	[CatalystActivity:10204779] hydroperoxy icosatetraenoate isomerase activity of ALOXE3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10204781
displayName	ALOXE3 isomerises 12R-HpETE to HXA3
eventOf	[Pathway:R-RNO-2142712] Synthesis of 12-eicosatetraenoic acid derivatives - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8942208] ALOXE3 isomerises 12R-HpETE to HXA3 - Homo sapiens
input	[SimpleEntity:R-ALL-2142790] 12R-HpETE [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALOXE3 isomerises 12R-HpETE to HXA3
output	[SimpleEntity:R-ALL-8942209] HXA3 [cytosol]
precedingEvent	[Reaction:R-RNO-2161950] Arachidonate is oxidised to 12R-HpETE by ALOX12B - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8942208
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2142712] Synthesis of 12-eicosatetraenoic acid derivatives
(inferredTo)	[Reaction:R-HSA-8942208] ALOXE3 isomerises 12R-HpETE to HXA3

Cite Us!