Reactome | HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10211570] protein serine/threonine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] [CatalystActivity:10199699] protein tyrosine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10199692
displayName	HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane]
hasComponent	[GenomeEncodedEntity:R-RNO-8857566] Ghost homologue of LINC01139 [cytosol] [Complex:R-RNO-8857556] HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] [EntityWithAccessionedSequence:R-RNO-5661173] LRRK2 [cytosol] [EntityWithAccessionedSequence:R-RNO-8857570] phospho-Ptk6 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8857574] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] - Homo sapiens
maxDepth	4
name	HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2
producedByEvent	[Reaction:R-RNO-8857577] LINC01139 facilitates PTK6 autophosphorylation - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8857574
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10211570] protein serine/threonine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane] [CatalystActivity:10199699] protein tyrosine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane]
(output)	[Reaction:R-RNO-8857577] LINC01139 facilitates PTK6 autophosphorylation
(inferredTo)	[Complex:R-HSA-8857574] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:p-Y351-PTK6:LRRK2 [plasma membrane]