Reactome | UBA6 conjugates ubiquitin to cytosolic E2 enzymes

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UBA6 conjugates ubiquitin to cytosolic E2 enzymes Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10198586
displayName	UBA6 conjugates ubiquitin to cytosolic E2 enzymes
eventOf	[Pathway:R-RNO-8866652] Synthesis of active ubiquitin: roles of E1 and E2 enzymes - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8852127] UBA6 conjugates ubiquitin to cytosolic E2 enzymes - Homo sapiens
input	[DefinedSet:R-RNO-8852061] E2 ubiquitin conjugating enzyme (UBA6 substrate) [cytosol] [Complex:R-RNO-8852097] Ub-Cys625-UBA6:ubiquitin adenylate [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	UBA6 conjugates ubiquitin to cytosolic E2 enzymes
output	[Complex:R-RNO-8864229] Ub:E2 (UBA6 substrate) [cytosol] [Complex:R-RNO-8852088] UBA6:ubiquitin adenylate [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8852127
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8866652] Synthesis of active ubiquitin: roles of E1 and E2 enzymes
(inferredTo)	[Reaction:R-HSA-8852127] UBA6 conjugates ubiquitin to cytosolic E2 enzymes

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