Reactome | Deamination at C6 position of adenosine in Editosome (ADAR2)

Schema > Reaction > Entries

Deamination at C6 position of adenosine in Editosome (ADAR2) Show undefined attributes

catalystActivity	[CatalystActivity:10110590] double-stranded RNA adenosine deaminase activity of ADAR2 homodimer [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10110592
displayName	Deamination at C6 position of adenosine in Editosome (ADAR2)
eventOf	[Pathway:R-RNO-75102] C6 deamination of adenosine - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-77615] Deamination at C6 position of adenosine in Editosome (ADAR2) - Homo sapiens
input	[Complex:R-RNO-77610] Editosome (ADAR2) complex [nucleoplasm] [SimpleEntity:R-ALL-113518] H2O [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Deamination at C6 position of adenosine in Editosome (ADAR2)
output	[Complex:R-RNO-77611] A to I edited RNA:Editosome (ADAR2) complex [nucleoplasm] [SimpleEntity:R-ALL-76230] NH3 [nucleoplasm]
precedingEvent	[Reaction:R-RNO-77613] Binding of ADAR2 homodimer to dsRNA duplex - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-77615
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-75102] C6 deamination of adenosine
(inferredTo)	[Reaction:R-HSA-77615] Deamination at C6 position of adenosine in Editosome (ADAR2)

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