Reactome | SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)

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SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10110229
displayName	SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
eventOf	[Pathway:R-RNO-77075] RNA Pol II CTD phosphorylation and interaction with CE - Rattus norvegicus [Pathway:R-RNO-72086] mRNA Capping - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-77077] Capping complex formation - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-3009372] phospho-p-SUPT5H [nucleoplasm] [Complex:R-RNO-77053] RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-77060] RNMT [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
output	[Complex:R-RNO-77061] CE:Pol II CTD:Spt5 complex [nucleoplasm]
precedingEvent	[Reaction:R-RNO-77068] Activation of GT - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-77073
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-72086] mRNA Capping [Pathway:R-RNO-77075] RNA Pol II CTD phosphorylation and interaction with CE
(precedingEvent)	[Reaction:R-RNO-77077] Capping complex formation
(inferredTo)	[Reaction:R-HSA-77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)

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