Reactome | 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde

Schema > Reaction > Entries

3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde Show undefined attributes

catalystActivity	[CatalystActivity:10105336] 3-hydroxyanthranilate 3,4-dioxygenase activity of HAAO [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10105338
displayName	3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde
eventOf	[Pathway:R-RNO-71240] Tryptophan catabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-71218] 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde - Homo sapiens
input	[SimpleEntity:R-ALL-30487] 3HAA [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde 3-hydroxyanthranilate + O2 => (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde
output	[SimpleEntity:R-ALL-36027] ACS [cytosol]
precedingEvent	[Reaction:R-RNO-71217] 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-71218
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-71240] Tryptophan catabolism
(inferredTo)	[Reaction:R-HSA-71218] 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde

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