Reactome | Transcriptional activation of p53 responsive genes

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224923
displayName	Transcriptional activation of p53 responsive genes
eventOf	[Pathway:R-RNO-69563] p53-Dependent G1 DNA Damage Response - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-RNO-69895] Transcriptional activation of cell cycle inhibitor p21 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-69560] Transcriptional activation of p53 responsive genes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Transcriptional activation of p53 responsive genes
precedingEvent	[Pathway:R-RNO-69541] Stabilization of p53 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-69560
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-69563] p53-Dependent G1 DNA Damage Response
(inferredTo)	[Pathway:R-HSA-69560] Transcriptional activation of p53 responsive genes

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