Reactome | PAMP:NOD oligomer:RIP2:NEMO [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-RNO-688137] RIP2 is K63 polyubiquitinated - Rattus norvegicus [Reaction:R-RNO-741386] RIP2 induces K63-linked ubiquitination of NEMO - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10143758
displayName	PAMP:NOD oligomer:RIP2:NEMO [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-RNO-168108] IKBKG [cytosol] [Complex:R-RNO-168409] PAMP:NOD oligomer:RIP2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-688994] PAMP:NOD oligomer:RIP2:NEMO [cytosol] - Homo sapiens
maxDepth	6
name	PAMP:NOD oligomer:RIP2:NEMO
producedByEvent	[Reaction:R-RNO-741411] CYLD deubiquitinates NEMO - Rattus norvegicus [Reaction:R-RNO-688136] TNFAIP3 (A20) deubiquitinates RIP2 - Rattus norvegicus [Reaction:R-RNO-622415] RIP2 binds NEMO - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-688994
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-741411] CYLD deubiquitinates NEMO [Reaction:R-RNO-688136] TNFAIP3 (A20) deubiquitinates RIP2 [Reaction:R-RNO-622415] RIP2 binds NEMO
(input)	[Reaction:R-RNO-741386] RIP2 induces K63-linked ubiquitination of NEMO [Reaction:R-RNO-688137] RIP2 is K63 polyubiquitinated
(inferredTo)	[Complex:R-HSA-688994] PAMP:NOD oligomer:RIP2:NEMO [cytosol]