Reactome | RNF111 ubiquitinates SUMOylated XPC

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RNF111 ubiquitinates SUMOylated XPC Show undefined attributes

catalystActivity	[CatalystActivity:10189378] ubiquitin protein ligase activity of RNF111 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10189380
displayName	RNF111 ubiquitinates SUMOylated XPC
eventOf	[Pathway:R-RNO-5696395] Formation of Incision Complex in GG-NER - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5689317] Formation of the pre-incision complex in GG-NER - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-6790487] RNF111 ubiquitinates SUMOylated XPC - Homo sapiens
input	[Complex:R-RNO-6790510] K63polyUb:C87-UBE2N:UBE2V2 [nucleoplasm] [Complex:R-RNO-6790468] Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RNF111 ubiquitinates SUMOylated XPC
output	[Complex:R-RNO-6790517] Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] [Complex:R-RNO-6790519] Ub,SUMO,K63polyUb:XPC:RAD23:CETN2 [nucleoplasm] [Complex:R-RNO-5682542] UBE2N:UBE2V2 [nucleoplasm]
precedingEvent	[Reaction:R-RNO-6790454] SUMOylation of XPC - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6790487
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5696395] Formation of Incision Complex in GG-NER
(precedingEvent)	[Reaction:R-RNO-5689317] Formation of the pre-incision complex in GG-NER
(inferredTo)	[Reaction:R-HSA-6790487] RNF111 ubiquitinates SUMOylated XPC