Reactome | GFUS dimer reduces GDP-KDGal to GDP-Fuc

Schema > Reaction > Entries

GFUS dimer reduces GDP-KDGal to GDP-Fuc Show undefined attributes

catalystActivity	[CatalystActivity:10189112] GDP-L-fucose synthase activity of GFUS dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10189114
displayName	GFUS dimer reduces GDP-KDGal to GDP-Fuc
eventOf	[Pathway:R-RNO-6787639] GDP-fucose biosynthesis - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-6787642] GFUS dimer reduces GDP-KDGal to GDP-Fuc - Homo sapiens
input	[SimpleEntity:R-ALL-6787646] GDP-KDGal [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GFUS dimer reduces GDP-KDGal to GDP-Fuc GDP-4-dehydro-6-deoxy-beta-L-galactose + NADPH + H+ = GDP-beta-L-fucose + NADP+
output	[SimpleEntity:R-ALL-742368] GDP-Fuc [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-RNO-6787623] GFUS dimer epimerises GDP-DHDMan to GDP-KDGal - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6787642
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-6787639] GDP-fucose biosynthesis
(precedingEvent)	[Reaction:R-RNO-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen
(inferredTo)	[Reaction:R-HSA-6787642] GFUS dimer reduces GDP-KDGal to GDP-Fuc

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