Reactome | ERCC6 binds stalled RNA Pol II

Schema > Reaction > Entries

ERCC6 binds stalled RNA Pol II Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10188078
displayName	ERCC6 binds stalled RNA Pol II
eventOf	[Pathway:R-RNO-6781823] Formation of TC-NER Pre-Incision Complex - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-6781833] ERCC8 (CSA) binds stalled RNA Pol II - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-6781840] ERCC6 binds stalled RNA Pol II - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-54429] Ercc6 [nucleoplasm] [Complex:R-RNO-6781822] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ERCC6 binds stalled RNA Pol II
output	[Complex:R-RNO-6781837] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-RNO-6781824] Active RNA Pol II complex transcribes lesion-containing DNA template - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6781840
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-6781823] Formation of TC-NER Pre-Incision Complex
(precedingEvent)	[Reaction:R-RNO-6781833] ERCC8 (CSA) binds stalled RNA Pol II
(inferredTo)	[Reaction:R-HSA-6781840] ERCC6 binds stalled RNA Pol II