Reactome | USP25 deubiquitinates DDX58

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10064809] cysteine-type deubiquitinase activity of USP25:PolyUb-DDX58 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10064811
displayName	USP25 deubiquitinates DDX58
eventOf	[Pathway:R-RNO-5689880] Ub-specific processing proteases - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5696564] USP25 deubiquitinates DDX58 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-RNO-6782844] USP25:PolyUb-DDX58 [cytosol]
isInDisease	false
isInferred	true
name	USP25 deubiquitinates DDX58
output	[DefinedSet:R-RNO-5689096] PolyUb [cytosol] [Complex:R-RNO-6782841] USP25:DDX58 [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5696564
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-5689880] Ub-specific processing proteases
(inferredTo)	[Reaction:R-HSA-5696564] USP25 deubiquitinates DDX58