Reactome | Autophagosome maturation

Schema > BlackBoxEvent > Entries

Autophagosome maturation Show undefined attributes

category	omitted
compartment	[Compartment:5683628] autophagosome membrane [Compartment:5679192] phagophore assembly site membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10183291
displayName	Autophagosome maturation
eventOf	[Pathway:R-RNO-1632852] Macroautophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2454713] autophagosome maturation
inferredFrom	[BlackBoxEvent:R-HSA-5682388] Autophagosome maturation - Homo sapiens
input	[Complex:R-RNO-5682873] LC3:PE [phagophore assembly site membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Autophagosome maturation
output	[Complex:R-RNO-5683631] LC3:PE [autophagosome membrane]
precedingEvent	[Reaction:R-RNO-5205663] LC3 binds the autophagosome membrane Atg5-Atg12 complex - Rattus norvegicus [Reaction:R-RNO-8959571] LC3 binds the autophagosome membrane Atg5-Atg12 complex - Rattus norvegicus [Reaction:R-RNO-5678490] ATG16L1 complex transfers LC3 from ATG3 to PE - Rattus norvegicus
regulatedBy	[PositiveRegulation:10183292] Positive regulation by 'UVRAG complex [cytosol]' [PositiveRegulation:10183293] Positive regulation by 'ESCRT-III [cytosol]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5682388
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1632852] Macroautophagy
(inferredTo)	[BlackBoxEvent:R-HSA-5682388] Autophagosome maturation