Reactome | WIPIs bind PI3P

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:5679192] phagophore assembly site membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10182863
displayName	WIPIs bind PI3P
eventOf	[Pathway:R-RNO-1632852] Macroautophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5676229] WIPIs bind PI3P - Homo sapiens
input	[SimpleEntity:R-ALL-5693050] PI3P [phagophore assembly site membrane] [CandidateSet:R-RNO-5678301] WIPI1,WIPI2,(WDR45,WDR45B) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	WIPIs bind PI3P
output	[Complex:R-RNO-5678302] WIPI1,WIPI2,(WDR45,WDR45B):PI3P [phagophore assembly site membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5676229
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-1632852] Macroautophagy
(inferredTo)	[Reaction:R-HSA-5676229] WIPIs bind PI3P