Reactome | Beclin-1 complex phosphorylates PtdIns

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Beclin-1 complex phosphorylates PtdIns Show undefined attributes

catalystActivity	[CatalystActivity:10182178] 1-phosphatidylinositol-3-kinase activity of ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10182180
displayName	Beclin-1 complex phosphorylates PtdIns
eventOf	[Pathway:R-RNO-1632852] Macroautophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5672012] Beclin-1 complex phosphorylates PtdIns - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-426639] PI [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Beclin-1 complex phosphorylates PtdIns
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-5676030] PI3P [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-RNO-5679205] ULK1 phosphorylates Beclin-1 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5672012
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1632852] Macroautophagy
(inferredTo)	[Reaction:R-HSA-5672012] Beclin-1 complex phosphorylates PtdIns

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