Reactome | SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10181618] GTPase activity of SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10181615
displayName	SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
hasComponent	[Complex:R-RNO-5665660] RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] [EntityWithAccessionedSequence:R-RNO-195131] Srgap2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5665803] SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] - Homo sapiens
maxDepth	6
name	SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin
producedByEvent	[Reaction:R-RNO-5665802] SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5665803
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments
(physicalEntity)	[CatalystActivity:10181618] GTPase activity of SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
(output)	[Reaction:R-RNO-5665802] SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin
(inferredTo)	[Complex:R-HSA-5665803] SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]

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