Reactome | FGFRL1 modulation of FGFR1 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224779
displayName	FGFRL1 modulation of FGFR1 signaling
eventOf	[Pathway:R-RNO-5654736] Signaling by FGFR1 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-5654511] FGFRL1 dimer binds FGFs - Rattus norvegicus [Reaction:R-RNO-5654510] FGFRL1 binds SPRED1/2 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-5658623] FGFRL1 modulation of FGFR1 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	FGFRL1 modulation of FGFR1 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5658623
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-5654736] Signaling by FGFR1
(inferredTo)	[Pathway:R-HSA-5658623] FGFRL1 modulation of FGFR1 signaling

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