Reactome | RCHY1 binds POLH

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10181149
displayName	RCHY1 binds POLH
eventOf	[Pathway:R-RNO-110320] Translesion Synthesis by POLH - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5655170] RCHY1 monoubiquitinates POLH - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-5655142] RCHY1 binds POLH - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-110287] Polh [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-5655134] RCHY1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RCHY1 binds POLH
output	[Complex:R-RNO-5655139] POLH:RCHY1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5655142
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-110320] Translesion Synthesis by POLH
(precedingEvent)	[Reaction:R-RNO-5655170] RCHY1 monoubiquitinates POLH
(inferredTo)	[Reaction:R-HSA-5655142] RCHY1 binds POLH

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