Reactome | Downstream signaling of activated FGFR1

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Downstream signaling of activated FGFR1 Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223049
displayName	Downstream signaling of activated FGFR1
eventOf	[Pathway:R-RNO-5654736] Signaling by FGFR1 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-RNO-5654693] FRS-mediated FGFR1 signaling - Rattus norvegicus [Pathway:R-RNO-5654219] Phospholipase C-mediated cascade: FGFR1 - Rattus norvegicus [Pathway:R-RNO-5654688] SHC-mediated cascade:FGFR1 - Rattus norvegicus [Pathway:R-RNO-5654689] PI-3K cascade:FGFR1 - Rattus norvegicus [Reaction:R-RNO-5656064] Activated FGFR1 binds FLRT1,2,3 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-5654687] Downstream signaling of activated FGFR1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Downstream signaling of activated FGFR1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5654687
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5654736] Signaling by FGFR1
(inferredTo)	[Pathway:R-HSA-5654687] Downstream signaling of activated FGFR1

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