Reactome | Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-5654286] Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5654729] p-CBL:GRB2 binds p-FRS2:activated FGFR2 - Rattus norvegicus [Reaction:R-RNO-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10165835
displayName	Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane]
hasComponent	[Complex:R-RNO-5654201] Activated FGFR2:p-FRS2 [plasma membrane] [EntityWithAccessionedSequence:R-RNO-162573] phospho-p-Y542,Y580-PTPN11 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654184] Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] - Homo sapiens
maxDepth	7
name	Activated FGFR2:p-FRS2:p-PTPN11
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5654184
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5654729] p-CBL:GRB2 binds p-FRS2:activated FGFR2 [Reaction:R-RNO-5654620] Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
(hasComponent)	[Complex:R-RNO-5654286] Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] [Complex:R-RNO-5654194] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-5654184] Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane]