Reactome | Me2K10-histone H3 [nucleoplasm]

Schema > CandidateSet > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-RNO-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 - Rattus norvegicus [Reaction:R-RNO-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 - Rattus norvegicus [Reaction:R-RNO-4827382] SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10173886
displayName	Me2K10-histone H3 [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-RNO-427378] Me2K10-HIST1H3A [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-RNO-427407] Me2K10-HIST2H3A [nucleoplasm] - Rattus norvegicus
inDisease	false
inferredFrom	[CandidateSet:R-HSA-5634724] Me2K10-histone H3 [nucleoplasm] - Homo sapiens
maxDepth	2
name	Me2K10-histone H3 Me2K10-replicative histone H3 Me2K10-HIST1H3A,Me2K10-HIST2H3A Me2K10-replication-dependent histone H3
producedByEvent	[Reaction:R-RNO-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 - Rattus norvegicus [Reaction:R-RNO-5634729] EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) - Rattus norvegicus
schemaClass	CandidateSet
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5634724

(input)	[Reaction:R-RNO-4724279] KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 [Reaction:R-RNO-5661115] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 [Reaction:R-RNO-4827382] SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9)
(output)	[Reaction:R-RNO-5661120] KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 [Reaction:R-RNO-5634729] EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9)
(inferredTo)	[CandidateSet:R-HSA-5634724] Me2K10-histone H3 [nucleoplasm]