Reactome | Nucleosome with H3K9me3 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-9856821] L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] - Rattus norvegicus [Complex:R-RNO-9011915] KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10179622
displayName	Nucleosome with H3K9me3 [nucleoplasm]
hasComponent	2 × [DefinedSet:R-RNO-5625750] H3K9me3 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-RNO-3451053] Hist1h4b [nucleoplasm] 2 × [CandidateSet:R-RNO-181899] Histone H2A [nucleoplasm] 2 × [CandidateSet:R-RNO-181911] Histone H2B [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5625748] Nucleosome with H3K9me3 [nucleoplasm] - Homo sapiens
maxDepth	4
name	Nucleosome with H3K9me3
producedByEvent	[Reaction:R-RNO-9844057] SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome - Rattus norvegicus [Reaction:R-RNO-9844006] SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5625748
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-RNO-9011915] KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] [Complex:R-RNO-9856821] L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] [Complex:R-RNO-9856756] Retroelement chromatin with H3K9me3 [nucleoplasm] [Complex:R-RNO-5625764] KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm]
(output)	[Reaction:R-RNO-9844057] SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome [Reaction:R-RNO-9844006] SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3)
(inferredTo)	[Complex:R-HSA-5625748] Nucleosome with H3K9me3 [nucleoplasm]

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