Reactome | VCP hexamer [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-9758092] NPLOC4:UFD1:VCP hexamer [cytosol] - Rattus norvegicus [Complex:R-RNO-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Rattus norvegicus [Complex:R-RNO-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] - Rattus norvegicus [Complex:R-RNO-8850590] Deglycosylation complex [endoplasmic reticulum membrane] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10176808
displayName	VCP hexamer [cytosol]
hasComponent	6 × [EntityWithAccessionedSequence:R-RNO-1181251] VCP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5362364] VCP hexamer [cytosol] - Homo sapiens
maxDepth	2
name	VCP hexamer
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5362364
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-RNO-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] [Complex:R-RNO-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-RNO-9758092] NPLOC4:UFD1:VCP hexamer [cytosol] [Complex:R-RNO-9755500] UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] [Complex:R-RNO-8866531] ERAD complex [endoplasmic reticulum membrane] [Complex:R-RNO-8850590] Deglycosylation complex [endoplasmic reticulum membrane]
(activeUnit)	[CatalystActivity:10176859] ABC-type transporter activity of ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(inferredTo)	[Complex:R-HSA-5362364] VCP hexamer [cytosol]

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