Reactome | NOX2 complex [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-5218774] NOX2 complex:RAC1:GTP [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10175320
displayName	NOX2 complex [plasma membrane]
hasComponent	[Complex:R-RNO-5218783] Cytochrome b-245 [plasma membrane] [EntityWithAccessionedSequence:R-RNO-1222296] Ncf1 [cytosol] [EntityWithAccessionedSequence:R-RNO-1222600] Ncf2 [cytosol] [EntityWithAccessionedSequence:R-RNO-1222707] Ncf4 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5218791] NOX2 complex [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[CandidateSet:R-RNO-9020391] RAC3 effectors [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9013178] RAC1 effectors [cytosol] - Rattus norvegicus
name	NOX2 complex
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5218791
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[CandidateSet:R-RNO-9013178] RAC1 effectors [cytosol] [CandidateSet:R-RNO-9020391] RAC3 effectors [cytosol]
(input)	[Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1
(hasComponent)	[Complex:R-RNO-5218774] NOX2 complex:RAC1:GTP [plasma membrane]
(inferredTo)	[Complex:R-HSA-5218791] NOX2 complex [plasma membrane]