Reactome | VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-5218793] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] - Rattus norvegicus [Complex:R-RNO-5218766] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5218847] PAK2 binds NCK - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10175148
displayName	VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-5218745] phospho-p-S21,Y420-FYN [cytosol] [Complex:R-RNO-5218798] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5218780] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane] - Homo sapiens
maxDepth	5
name	VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN
producedByEvent	[Reaction:R-RNO-5218854] p-Y420-FYN is phosphorylated on S21 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5218780
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-RNO-5218793] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] [Complex:R-RNO-5218792] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] [Complex:R-RNO-5218782] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane] [Complex:R-RNO-5218766] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane]
(input)	[Reaction:R-RNO-5218847] PAK2 binds NCK
(output)	[Reaction:R-RNO-5218854] p-Y420-FYN is phosphorylated on S21
(inferredTo)	[Complex:R-HSA-5218780] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane]

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