Reactome | DNMT3A binds Me2sR4-HIST1H4

Schema > Reaction > Entries

DNMT3A binds Me2sR4-HIST1H4 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10175111
displayName	DNMT3A binds Me2sR4-HIST1H4
eventOf	[Pathway:R-RNO-3214858] RMTs methylate histone arginines - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5212679] DNMT3A binds Me2sR4-HIST1H4 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-212287] DNMT3A [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-4754243] H4c16 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	DNMT3A binds Me2sR4-HIST1H4
output	[Complex:R-RNO-5218928] Me2R4-HIST1H4:DNMT3A [nucleoplasm]
precedingEvent	[Reaction:R-RNO-5205861] COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5212679
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3214858] RMTs methylate histone arginines
(inferredTo)	[Reaction:R-HSA-5212679] DNMT3A binds Me2sR4-HIST1H4

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