Reactome | PRMT1,PRMT6 methylate arginine-4 of histone H4

Schema > Reaction > Entries

PRMT1,PRMT6 methylate arginine-4 of histone H4 Show undefined attributes

catalystActivity	[CatalystActivity:10174925] protein-arginine N-methyltransferase activity of PRMT1,PRMT6 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10174927
displayName	PRMT1,PRMT6 methylate arginine-4 of histone H4
eventOf	[Pathway:R-RNO-3214858] RMTs methylate histone arginines - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5205798] PRMT1,PRMT6 methylate arginine-4 of histone H4 - Homo sapiens
input	[SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-3451053] Hist1h4b [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PRMT1,PRMT6 methylate arginine-4 of histone H4
output	[SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-4754240] H4c16 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5205798
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3214858] RMTs methylate histone arginines
(inferredTo)	[Reaction:R-HSA-5205798] PRMT1,PRMT6 methylate arginine-4 of histone H4

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