Reactome | GRIK3 homomer binds glutamate

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10143083
displayName	GRIK3 homomer binds glutamate
eventOf	[Pathway:R-RNO-500657] Presynaptic function of Kainate receptors - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-500708] GRIK3 homomer binds glutamate - Homo sapiens
input	[Complex:R-RNO-450196] GRIK 3 homomer [plasma membrane] [SimpleEntity:R-ALL-210382] L-Glu [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GRIK3 homomer binds glutamate
output	[Complex:R-RNO-500705] GRIK3 homomer glutamate complex [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-500708
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-500657] Presynaptic function of Kainate receptors
(inferredTo)	[Reaction:R-HSA-500708] GRIK3 homomer binds glutamate

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