Reactome | Exocytosis of platelet alpha granule contents

Schema > Reaction > Entries

Exocytosis of platelet alpha granule contents Show undefined attributes

category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10142705
displayName	Exocytosis of platelet alpha granule contents
eventOf	[Pathway:R-RNO-114608] Platelet degranulation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-9669959] Factor IXa binds protein S - Rattus norvegicus [Reaction:R-RNO-158340] kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin - Rattus norvegicus [Reaction:R-RNO-9653879] factor XIIa binds HRG - Rattus norvegicus [Reaction:R-RNO-9657706] factor XIa binds APP(18-770) - Rattus norvegicus [Reaction:R-RNO-9655851] factor XIa binds SERPINE1 - Rattus norvegicus [Reaction:R-RNO-9653838] factor XIa binds SERPING1 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-481007] Exocytosis of platelet alpha granule contents - Homo sapiens
input	[DefinedSet:R-RNO-481003] Platelet alpha granule contents [platelet alpha granule lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Exocytosis of platelet alpha granule contents
output	[DefinedSet:R-RNO-481033] Platelet alpha granule contents [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-481007
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-114608] Platelet degranulation
(precedingEvent)	[Reaction:R-RNO-9657706] factor XIa binds APP(18-770) [Reaction:R-RNO-9655851] factor XIa binds SERPINE1 [Reaction:R-RNO-9653838] factor XIa binds SERPING1 [Reaction:R-RNO-9669959] Factor IXa binds protein S [Reaction:R-RNO-9653879] factor XIIa binds HRG [Reaction:R-RNO-158340] kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin
(inferredTo)	[Reaction:R-HSA-481007] Exocytosis of platelet alpha granule contents