Reactome | RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1

Schema > Reaction > Entries

RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 Show undefined attributes

catalystActivity	[CatalystActivity:10168873] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]
category	transition
compartment	[Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10173440
displayName	RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1
eventOf	[Pathway:R-RNO-4570464] SUMOylation of RNA binding proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4570493] RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-71933] Hnrnpc [nucleoplasm] [Complex:R-RNO-2993783] SUMO1:C93-UBE2I [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1
output	[EntityWithAccessionedSequence:R-RNO-4570543] Hnrnpc [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-912481] Ube2i [nucleoplasm]
precedingEvent	[Reaction:R-RNO-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-4570493
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-4570464] SUMOylation of RNA binding proteins
(inferredTo)	[Reaction:R-HSA-4570493] RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1

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