Reactome | IRAK1 induces oligomerisation of TRAF6

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141542
displayName	IRAK1 induces oligomerisation of TRAF6
eventOf	[Pathway:R-RNO-9020702] Interleukin-1 signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-450173] IRAK1 induces oligomerisation of TRAF6 - Homo sapiens
input	[Complex:R-RNO-450121] p-2S,S376,T,T209,T387-IRAK1:TRAF6 [cytosol] 2 × [EntityWithAccessionedSequence:R-RNO-166366] Traf6 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	IRAK1 induces oligomerisation of TRAF6
output	[Complex:R-RNO-450159] hp-IRAK1:3xTRAF6 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-450173
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-450173] IRAK1 induces oligomerisation of TRAF6

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