Reactome | IL34 dimerizes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141090
displayName	IL34 dimerizes
eventOf	[Pathway:R-RNO-449836] Other interleukin signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-9009558] IL34 dimer binds SDC1 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-448632] IL34 dimerizes - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-RNO-448636] Il34 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IL34 dimerizes Interleukin-34 is a homodimer
output	[Complex:R-RNO-448628] IL34 dimer [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-448632
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-449836] Other interleukin signaling
(precedingEvent)	[Reaction:R-RNO-9009558] IL34 dimer binds SDC1
(inferredTo)	[Reaction:R-HSA-448632] IL34 dimerizes

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