Reactome | Cell-extracellular matrix interactions

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Cell-extracellular matrix interactions Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223819
displayName	Cell-extracellular matrix interactions
eventOf	[Pathway:R-RNO-446728] Cell junction organization - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-RNO-446343] Localization of the PINCH-ILK-PARVIN complex to focal adhesions - Rattus norvegicus [Pathway:R-RNO-446388] Regulation of cytoskeletal remodeling and cell spreading by IPP complex components - Rattus norvegicus [Reaction:R-RNO-430341] Mig-2 recruits Migfilin to the cell-ECM adhesions - Rattus norvegicus [Reaction:R-RNO-430347] MigFilin associates with Filamin and F-actin - Rattus norvegicus [Reaction:R-RNO-446364] Migfilin interacts with VASP - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-446353] Cell-extracellular matrix interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Cell-extracellular matrix interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-446353
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-446728] Cell junction organization
(inferredTo)	[Pathway:R-HSA-446353] Cell-extracellular matrix interactions

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