Reactome | Calcium Binds Caldesmon

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10140505
displayName	Calcium Binds Caldesmon
eventOf	[Pathway:R-RNO-445355] Smooth Muscle Contraction - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-445705] Release Of ADP From Myosin - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-445704] Calcium Binds Caldesmon - Homo sapiens
input	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol] [Complex:R-RNO-445703] Inactive Myosin Actin Contractile Complex [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Calcium Binds Caldesmon
output	[Complex:R-RNO-445702] Calcium Bound Myosin Actin Complex [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-445704
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-445355] Smooth Muscle Contraction
(precedingEvent)	[Reaction:R-RNO-445705] Release Of ADP From Myosin
(inferredTo)	[Reaction:R-HSA-445704] Calcium Binds Caldesmon

Cite Us!