Reactome | SLC-mediated transport of neurotransmitters

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SLC-mediated transport of neurotransmitters Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223491
displayName	SLC-mediated transport of neurotransmitters
eventOf	[Pathway:R-RNO-425407] SLC-mediated transmembrane transport - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22502] neurotransmitter transport
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-RNO-444007] GAT1-3 mediate Na+/Cl- dependent GABA transport - Rattus norvegicus [Reaction:R-RNO-374896] Uptake of Noradrenaline - Rattus norvegicus [Reaction:R-RNO-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-379393] SLC6A3 cotransports DA, Na+, Cl- from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-380620] Reuptake of serotonin from the synapse - Rattus norvegicus [Reaction:R-RNO-444120] SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-444100] PROT mediates L-proline uptake - Rattus norvegicus [Reaction:R-RNO-375487] SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-352059] SLC6A15-mediated amino acid uptake - Rattus norvegicus [Reaction:R-RNO-375473] SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-428625] Vesicular inhibitory amino acid transport - Rattus norvegicus [Reaction:R-RNO-428052] SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ - Rattus norvegicus [Reaction:R-RNO-8875623] SLC25A18,22 import L-Glu, H+ - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SLC-mediated transport of neurotransmitters
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-442660
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-425407] SLC-mediated transmembrane transport
(inferredTo)	[Pathway:R-HSA-442660] SLC-mediated transport of neurotransmitters

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