Reactome | Organic anion transport by SLC5/17/25 transporters

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Organic anion transport by SLC5/17/25 transporters Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222273
displayName	Organic anion transport by SLC5/17/25 transporters
eventOf	[Pathway:R-RNO-9955298] SLC-mediated transport of organic anions - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-429749] SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Rattus norvegicus [Reaction:R-RNO-8876312] SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-428585] SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol - Rattus norvegicus [Reaction:R-RNO-372843] SLC25A10 mediates exchange of malate and phosphate - Rattus norvegicus [Reaction:R-RNO-75849] SLC25A1 exchanges CIT and MAL - Rattus norvegicus [Reaction:R-RNO-372449] SLC25A1 may exchange mitochondrial PEP for cytosolic anion - Rattus norvegicus [Reaction:R-RNO-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-428643] Organic anion transport by SLC5/17/25 transporters - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Organic anion transport by SLC5/17/25 transporters
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-428643
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9955298] SLC-mediated transport of organic anions
(inferredTo)	[Pathway:R-HSA-428643] Organic anion transport by SLC5/17/25 transporters

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