Reactome | Ca permeable AMPA receptor ligand binding

Schema > Reaction > Entries

Ca permeable AMPA receptor ligand binding Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10137444
displayName	Ca permeable AMPA receptor ligand binding
eventOf	[Pathway:R-RNO-399710] Activation of AMPA receptors - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-399712] Activation of Ca permeable AMPA receptors - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-420977] Ca permeable AMPA receptor ligand binding - Homo sapiens
input	[DefinedSet:R-RNO-399714] Ca permeable AMPA receptors [plasma membrane] [SimpleEntity:R-ALL-210382] L-Glu [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Ca permeable AMPA receptor ligand binding
output	[Complex:R-RNO-420976] Ca permeable AMPA receptor ligand complex [plasma membrane]
precedingEvent	[Reaction:R-RNO-416320] Trafficking of GluR1-containing AMPA receptors - Rattus norvegicus [Reaction:R-RNO-210430] Release of L-Glutamate at the synapse - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-420977
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-399710] Activation of AMPA receptors
(precedingEvent)	[Reaction:R-RNO-399712] Activation of Ca permeable AMPA receptors
(inferredTo)	[Reaction:R-HSA-420977] Ca permeable AMPA receptor ligand binding

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