Reactome | ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen

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ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen Show undefined attributes

catalystActivity	[CatalystActivity:10136633] P-type calcium transporter activity of ATP2A1-3 [platelet dense tubular network membrane]
category	transition
compartment	[Compartment:114521] platelet dense tubular network membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10136635
displayName	ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen
eventOf	[Pathway:R-RNO-418359] Reduction of cytosolic Ca++ levels - Rattus norvegicus [Pathway:R-RNO-936837] Ion transport by P-type ATPases - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-418365] ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen - Homo sapiens
input	2 × [SimpleEntity:R-ALL-74016] Ca2+ [cytosol] 2 × [SimpleEntity:R-ALL-427899] H+ [platelet dense tubular network lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen Sequestration of Ca2+ to dense tubular network lumen
output	2 × [SimpleEntity:R-ALL-139827] Ca2+ [platelet dense tubular network lumen] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-418365
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-418359] Reduction of cytosolic Ca++ levels [Pathway:R-RNO-936837] Ion transport by P-type ATPases
(inferredTo)	[Reaction:R-HSA-418365] ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen

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