Reactome | Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1)

Schema > BlackBoxEvent > Entries

Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) Show undefined attributes

catalystActivity	[CatalystActivity:10136573] protein tyrosine kinase activity of F2R:ARRB1:MAPKs:active SRC-1 [plasma membrane]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10136575
displayName	Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1)
eventOf	[Pathway:R-RNO-456926] Thrombin signalling through proteinase activated receptors (PARs) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-418163] Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) - Homo sapiens
input	[Complex:R-RNO-418103] F2R:ARRB1:MAPKs:SRC-1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1)
output	[Complex:R-RNO-418210] F2R:ARRB1:active MAPKs:active SRC-1 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-RNO-418158] SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-418163
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-456926] Thrombin signalling through proteinase activated receptors (PARs)
(inferredTo)	[BlackBoxEvent:R-HSA-418163] Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1)

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