Reactome | G-protein beta:gamma signalling

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223347
displayName	G-protein beta:gamma signalling
eventOf	[Pathway:R-RNO-388396] GPCR downstream signalling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-392451] G beta:gamma signalling through PI3Kgamma - Rattus norvegicus [Pathway:R-RNO-8964616] G beta:gamma signalling through CDC42 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-397795] G-protein beta:gamma signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	G-protein beta:gamma signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-397795
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-388396] GPCR downstream signalling
(hasEncapsulatedEvent)	[Pathway:R-RNO-418555] G alpha (s) signalling events [Pathway:R-RNO-416476] G alpha (q) signalling events [Pathway:R-RNO-416482] G alpha (12/13) signalling events [Pathway:R-RNO-418594] G alpha (i) signalling events [Pathway:R-RNO-418597] G alpha (z) signalling events
(inferredTo)	[Pathway:R-HSA-397795] G-protein beta:gamma signalling

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