Reactome | p-EFNB binds GRB4

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10172355
displayName	p-EFNB binds GRB4
eventOf	[Pathway:R-RNO-3928664] Ephrin signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3928639] p-EFNB binds GRB4 - Homo sapiens
input	[Complex:R-RNO-3928510] EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] [EntityWithAccessionedSequence:R-RNO-204885] Nck2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-EFNB binds GRB4
output	[Complex:R-RNO-3928522] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3928639
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-3928664] Ephrin signaling
(inferredTo)	[Reaction:R-HSA-3928639] p-EFNB binds GRB4