Reactome | Adrenaline signalling through Alpha-2 adrenergic receptor

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223655
displayName	Adrenaline signalling through Alpha-2 adrenergic receptor
eventOf	[Pathway:R-RNO-76009] Platelet Aggregation (Plug Formation) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20684] platelet activation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-390663] ADRA2A,B,C bind ADR,NAd - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-392023] Adrenaline signalling through Alpha-2 adrenergic receptor - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Adrenaline signalling through Alpha-2 adrenergic receptor
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-392023
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-76009] Platelet Aggregation (Plug Formation)
(inferredTo)	[Pathway:R-HSA-392023] Adrenaline signalling through Alpha-2 adrenergic receptor

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