Reactome | Calcium Binds Troponin-C

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10135248
displayName	Calcium Binds Troponin-C
eventOf	[Pathway:R-RNO-390522] Striated Muscle Contraction - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-390598] Myosin Binds ATP - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-390595] Calcium Binds Troponin-C - Homo sapiens
input	4 × [SimpleEntity:R-ALL-74016] Ca2+ [cytosol] [Complex:R-RNO-390590] Inactive Sarcomere Protein Complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Calcium Binds Troponin-C
output	[Complex:R-RNO-390592] Calcium Bound Sarcomere Protein Complex [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-390595
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-390522] Striated Muscle Contraction
(precedingEvent)	[Reaction:R-RNO-390598] Myosin Binds ATP
(inferredTo)	[Reaction:R-HSA-390595] Calcium Binds Troponin-C

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