Reactome | phospho CD28:B7-1/B7-2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-389384] CD28:GRAP2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-389381] Gads binds CD28 - Rattus norvegicus [Reaction:R-RNO-388814] Grb2 binds CD28 - Rattus norvegicus [Reaction:R-RNO-388832] PI3K binds CD28 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10134511
displayName	phospho CD28:B7-1/B7-2 [plasma membrane]
hasComponent	[DefinedSet:R-RNO-388762] B7-1 homodimer/ B7-2 [plasma membrane] 2 × [DefinedSet:R-RNO-2395419] FYN,LCK [cytosol] [Complex:R-RNO-388778] Phospho CD28 homodimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-388777] phospho CD28:B7-1/B7-2 [plasma membrane] - Homo sapiens
maxDepth	4
name	phospho CD28:B7-1/B7-2
producedByEvent	[Reaction:R-RNO-388831] Phosphorylation of CD28 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-388777
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-389381] Gads binds CD28 [Reaction:R-RNO-388814] Grb2 binds CD28 [Reaction:R-RNO-388832] PI3K binds CD28
(hasComponent)	[Complex:R-RNO-389384] CD28:GRAP2 [plasma membrane] [Complex:R-RNO-388786] CD28:Grb2 [plasma membrane] [Complex:R-RNO-388783] CD28:PI3K [plasma membrane]
(output)	[Reaction:R-RNO-388831] Phosphorylation of CD28
(inferredTo)	[Complex:R-HSA-388777] phospho CD28:B7-1/B7-2 [plasma membrane]