Reactome | Enzymatic degradation of Dopamine by monoamine oxidase

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Enzymatic degradation of Dopamine by monoamine oxidase Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223567
displayName	Enzymatic degradation of Dopamine by monoamine oxidase
eventOf	[Pathway:R-RNO-379401] Dopamine clearance from the synaptic cleft - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:12107] dopamine catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-379382] MAOA:FAD deaminates DA to DOPAC - Rattus norvegicus [Reaction:R-RNO-379464] COMT transfers Met to DOPAC to form HVA - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-379398] Enzymatic degradation of Dopamine by monoamine oxidase - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Enzymatic degradation of Dopamine by monoamine oxidase
precedingEvent	[Reaction:R-RNO-379393] SLC6A3 cotransports DA, Na+, Cl- from extracellular region to cytosol - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-379398
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-379401] Dopamine clearance from the synaptic cleft
(inferredTo)	[Pathway:R-HSA-379398] Enzymatic degradation of Dopamine by monoamine oxidase

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