Reactome | Fibronectin degradation by CTSG

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10171710] serine-type endopeptidase activity of CTSG [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10171712
displayName	Fibronectin degradation by CTSG
eventOf	[Pathway:R-RNO-1474228] Degradation of the extracellular matrix - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3785684] Fibronectin degradation by CTSG - Homo sapiens
input	[Polymer:R-RNO-2327729] Fibronectin matrix [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Fibronectin degradation by CTSG
output	[Polymer:R-RNO-2533900] Cleaved fibronectin matrix [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3785684
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-1474228] Degradation of the extracellular matrix
(inferredTo)	[Reaction:R-HSA-3785684] Fibronectin degradation by CTSG

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