Reactome | p130Cas linkage to MAPK signaling for integrins

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223505
displayName	p130Cas linkage to MAPK signaling for integrins
eventOf	[Pathway:R-RNO-354192] Integrin signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-372705] Recruitment of BCAR1 to PTK2 complex - Rattus norvegicus [Reaction:R-RNO-372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - Rattus norvegicus [Reaction:R-RNO-372697] Crk binding to p130cas - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-372708] p130Cas linkage to MAPK signaling for integrins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	p130Cas linkage to MAPK signaling for integrins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-372708
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-354192] Integrin signaling
(inferredTo)	[Pathway:R-HSA-372708] p130Cas linkage to MAPK signaling for integrins

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