Reactome | RNF146 binds RibC-AXIN:TNKS complex

Schema > Reaction > Entries

RNF146 binds RibC-AXIN:TNKS complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10171124
displayName	RNF146 binds RibC-AXIN:TNKS complex
eventOf	[Pathway:R-RNO-4641257] Degradation of AXIN - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-3640861] RNF146 ubiquitinates ADP-ribosylated AXIN - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-3640844] RNF146 binds RibC-AXIN:TNKS complex - Homo sapiens
input	[Complex:R-RNO-3772504] RibC-AXIN:TNKS [cytosol] [EntityWithAccessionedSequence:R-RNO-3640827] RNF146 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RNF146 binds RibC-AXIN:TNKS complex
output	[Complex:R-RNO-3640845] RibC-AXIN:TNKS:RNF146 [cytosol]
precedingEvent	[Reaction:R-RNO-3640858] Tankyrase ADP-ribosylates AXIN - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3640844
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-4641257] Degradation of AXIN
(precedingEvent)	[Reaction:R-RNO-3640861] RNF146 ubiquitinates ADP-ribosylated AXIN
(inferredTo)	[Reaction:R-HSA-3640844] RNF146 binds RibC-AXIN:TNKS complex

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